This research work was carried out on security measures and challenges in information resources in Federal University of Technology, Owerri library in Imo State. Five purposes of study and corresponding research questions were posed to guide the study. The survey design was adopted in this study and the population was the 54 professional and para-professionals who were also used as the sample. The data collected were analysed using frequency table and simple percentages. The revealed that theft, mutilation and defacement are the major crimes committed in the library, textbooks and reference materials are prone to security challenges, security measures adopted by the library are installation of security cameras, stamping of library materials, searching of library users among others. The researcher recommended that the library management should acquire more information materials to prevent theft and mutilation, more sophisticated security devices such as CCTV should be employed and skilled security personnel should be employed.